Because the match ends the exact millisecond a tower hits zero hitpoints, certain cards become exponentially more valuable, while others become complete liabilities.

This article analyzes the absolute best cards to have in your rotation when the Overtime clock begins ticking down.
The Unblockable Finishers: Heavy Spells
You completely abandon all ground attacks and simply launch massive damage spells directly at their tower while defending flawlessly.

If you know your opponent's tower is at 550 health, and you have a Rocket in your hand, you have already mathematically won the game.
The Fireball is great for chip damage, but it takes 3 or 4 cycles to kill a healthy tower in overtime.If the opponent is spell cycling you, you must pressure them so heavily they cannot afford to spend 6 elixir on a spell.If you cast Poison, they might cast a Rocket and win before your Poison finishes ticking. Instant Deployers and Bridge Threats
If you do not have a heavy spell, or the tower health is too high to spell cycle, you must rely on units that can guarantee near-instant damage.

Similarly, fast 'Bridge Spam' units like the Bandit or the Royal Ghost are terrifying in Overtime.
Sudden Death CardThe Overtime AdvantageRisk LevelThe MinerCan be placed instantly anywhere; bypasses all ground defenses and guarantees chip damage if the opponent predicts wrongLow Risk; only costs 3 elixir, leaving plenty of energy for defenseThe Freeze SpellStops all enemy defenses for 4 seconds; if you have even a single Skeleton near their tower, Freeze guarantees massive damageExtreme Risk; if it fails to take the tower, you wasted 4 elixir and they have a massive counter-push ready Staying Cold Under Pressure
The player who panics and throws a desperate, unsupported push will almost always lose to the player who calmly executes their win condition.

Be the player who calculates the win.

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