Your defensive structure acts as the anchor of your entire strategy, dictating exactly what types of enemy pushes you can comfortably survive.

Making the wrong choice will leave a glaring weakness in your roster that experienced opponents will ruthlessly exploit.
Melting the Behemoths
Single-target defenses, such as the Inferno Tower or the Cannon, are designed specifically to deal with massive, high-hitpoint threats.

A single-target tower will waste its massive damage output slowly killing one skeleton at a time, allowing the main enemy tank to slip by completely unharmed.
Ensure the tower locks onto the tank.Place the building in the center to pull the tank across both lanes.You must bait out their stun first. The Splash Damage Swarm Sweepers
A Bomb Tower placed in the center of the arena can single-handedly stop a massive, ten-elixir swarm push while taking minimal damage.

The trade-off is that these buildings possess incredibly low single-target Damage Per Second (DPS).
Defense CategoryBest AgainstBiggest WeaknessHigh DPS BuildingMelts high health units instantly if unprotectedWastes time killing cheap units one by oneSwarm SweeperMassive ground swarms, bridge spam, bait decksLacks the raw damage to stop a massive push Making the Final Choice
If you already run three area-of-effect spells, you probably do not need a splash damage building; take a single-target killer instead.

Master the placements of both architectural styles, and you will construct an impenetrable fortress.

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